Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301692 | 0.82 | CACNA1G (0.49) | MDM2MCL1BCL2PTGS2MEN1 | |
| SCHEMBL8593794 | 0.82 | CACNA1G (0.49) | MDM2MCL1BCL2PTGS2MEN1 | |
| SCHEMBL8591001 | 0.76 | CACNA1G (0.55) | MDM2MCL1BCL2MEN1KMT2A | |
| SCHEMBL8591003 | 0.76 | CACNA1G (0.55) | MDM2MCL1BCL2MEN1KMT2A | |
| SCHEMBL8591058 | 0.72 | RPA1 (0.73) | MDM2MCL1BCL2MEN1KMT2A | |
| SCHEMBL8296254 | 0.71 | CACNA1G (0.46) | MDM2MCL1BCL2PTGS2MEN1 | |
| SCHEMBL8296252 | 0.71 | CACNA1G (0.46) | MDM2MCL1BCL2PTGS2MEN1 | |
| SCHEMBL8590028 | 0.70 | PPP1CA (0.59) | MDM2MCL1BCL2MEN1KMT2A | |
| SCHEMBL15636168 | 0.69 | CTSA (0.57) | CTSACACNA1GCACNA1H | |
| SCHEMBL8294446 | 0.68 | CACNA1G (0.45) | MDM2MCL1BCL2PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477049-B1 | Amido-3-pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 1999-12-01 | — | — | EP | claimed |