Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RPA1 | P27694 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | BCL2 | P10415 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MARS1 | P56192 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591058 | 0.89 | RPA1 (0.73) | PPP1CAL3MBTL1RPA1MEN1KMT2A | |
| SCHEMBL27882807 | 0.76 | RAB9A (0.71) | L3MBTL1SMN1; SMN2CA1CA2CA9 | |
| SCHEMBL24157617 | 0.76 | CYP2C9 (0.49) | RPA1MEN1KMT2AMCL1SMN1; SMN2 | |
| SCHEMBL8591003 | 0.75 | CACNA1G (0.55) | PPP1CARPA1MEN1KMT2AMALT1 | |
| SCHEMBL8591001 | 0.75 | CACNA1G (0.55) | PPP1CARPA1MEN1KMT2AMALT1 | |
| SCHEMBL4500796 | 0.73 | L3MBTL1 (1.00) | PPP1CAL3MBTL1RPA1MEN1KMT2A | |
| SCHEMBL695352 | 0.73 | RPA1 (1.00) | PPP1CAL3MBTL1RPA1MEN1KMT2A | |
| SCHEMBL4093659 | 0.73 | KDM4E (0.60) | PPP1CAL3MBTL1RPA1MEN1KMT2A | |
| SCHEMBL6457030 | 0.73 | MARS1 (0.62) | PPP1CAL3MBTL1RPA1MEN1KMT2A | |
| SCHEMBL3851459 | 0.72 | RAB9A (0.51) | PPP1CAL3MBTL1RPA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744493-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5744491-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5635526-A | POSSESSES ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM OR THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1997-06-03 | — | — | US | disclosed |
| US-5607958-A | NEUROTENSIN RECEPTOR BINDERS | SANOFI (FR) | 1997-03-04 | — | — | US | disclosed |
| US-5420141-A | Capable of binding to neurotensin receptor | SANOFI (FR) | 1995-05-30 | — | — | US | disclosed |