Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.55 |
| ▸ | BCHE | P06276 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14476118 | 0.83 | ACHE (0.54) | ACHEBCHEDRD2DRD4 | |
| SCHEMBL9477536 | 0.83 | ACHE (0.69) | ACHEBCHEDRD2DRD4 | |
| SCHEMBL26371335 | 0.82 | BCHE (0.47) | ACHEBCHEDRD4 | |
| SCHEMBL7507555 | 0.81 | SIGMAR1 (0.51) | ACHEBCHEDRD2 | |
| SCHEMBL3815654 | 0.81 | SIGMAR1 (0.51) | ACHEBCHEDRD2 | |
| SCHEMBL18105283 | 0.80 | MEN1 (0.55) | ACHEBCHE | |
| SCHEMBL8567376 | 0.80 | CCR5 (0.52) | ACHEBCHE | |
| SCHEMBL10025921 | 0.80 | BCHE (0.48) | ACHEBCHE | |
| SCHEMBL2148529 | 0.80 | BCHE (0.48) | ACHEBCHEDRD2 | |
| SCHEMBL4918559 | 0.80 | CHRM3 (0.56) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244758-B2 | N-type calcium channel blockers | NEUROMED PHARMACEUTICALS LTD. (CA) | 2007-07-17 | — | — | US | disclosed |
| WO-2004105750-A1 | 3-AMINOMETHYL-PYRROLIDINES AS N-TYPE CALCIUM CHANNEL BLOCKERS | NEUROMED TECHNOLOGIES, INC. (CA) | 2004-12-09 | — | — | WO | disclosed |