Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | MST1R | Q04912 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592814 | 0.98 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL8593588 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL28547668 | 0.83 | EDNRA (0.47) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL8592813 | 0.83 | HSD17B10 (0.41) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL8298169 | 0.79 | MAPT (0.38) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL8589908 | 0.78 | MAPT (0.38) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL8593607 | 0.75 | TTR (0.39) | ALDH1A1HSD17B10TSHRTTRSTAT3 | |
| SCHEMBL599747 | 0.74 | TTR (0.59) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL15365507 | 0.73 | TDO2 (0.46) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL3478457 | 0.73 | SCN9A (0.49) | EDNRASTAT3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1238765-A | N-(imidazoly (butyl) benzenesulphonamide derivatives with anticoagulation active | SYNTHEBLABO (FR) | 1999-12-15 | — | — | CN | disclosed |
| EP-0713865-B1 | 2-Aminobenzenesulphonic acid and 2-aminobenzenesulphonyl chloride derivatives, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1999-02-10 | — | — | EP | disclosed |
| US-5753667-A | ANTITHROMBOSIS | SYNTHELABO (FR) | 1998-05-19 | — | — | US | disclosed |
| US-5602149-A | TREATING OR PREVENTING THROMBOSIS | SYNTHELABO (FR) | 1997-02-11 | — | — | US | disclosed |
| EP-0713865-A1 | 2-Aminobenzenesulphonic acid and 2-aminobenzenesulphonyl chloride derivatives, their preparation and their use as synthetic intermediates | SYNTHELABO (FR) | 1996-05-29 | — | — | EP | disclosed |