Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | MST1R | Q04912 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198693 | 0.83 | EDNRA (0.51) | EDNRALTA4HSCN9AKDM4EALDH1A1 | |
| SCHEMBL8298599 | 0.83 | ALDH1A1 (0.42) | EDNRALTA4HKDM4EALDH1A1GAA | |
| SCHEMBL8592814 | 0.82 | ALDH1A1 (0.41) | EDNRALTA4HKDM4EALDH1A1GAA | |
| SCHEMBL7950052 | 0.81 | EDNRA (0.47) | EDNRALTA4HSCN9AKDM4EALDH1A1 | |
| SCHEMBL3478457 | 0.81 | SCN9A (0.49) | EDNRASCN9A | |
| SCHEMBL15518348 | 0.80 | EDNRA (0.46) | EDNRALTA4HSCN9AKDM4EALDH1A1 | |
| SCHEMBL27753938 | 0.78 | MAOA (0.46) | EDNRAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5446955 | 0.78 | MAOA (0.46) | EDNRAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL458284 | 0.77 | SMN1; SMN2 (0.48) | KDM4EGAAMAPTTSHRPGAM1 | |
| SCHEMBL10623296 | 0.76 | EDNRA (0.49) | EDNRALTA4HSCN9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112442002-B | Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound | 桂林医学院 | 2022-09-20 | — | — | CN | disclosed |
| CN-112442002-A | Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound | 桂林医学院 | 2021-03-05 | — | — | CN | disclosed |