Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298169 | 0.99 | MAPT (0.38) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8589906 | 0.83 | FTO (0.44) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8592814 | 0.80 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8298599 | 0.78 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8593940 | 0.75 | AKR1C3 (0.44) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28547668 | 0.71 | EDNRA (0.47) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8590358 | 0.70 | CFTR (0.36) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8516341 | 0.69 | CA1 (0.40) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL6936181 | 0.68 | CA1 (0.43) | MAPTKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL27753938 | 0.68 | MAOA (0.46) | MAPTKDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739382-A | INTERMEDIATES FOR ANTICOAGULANTS | SYNTHELABO (FR) | 1998-04-14 | — | — | US | disclosed |
| US-5712393-A | FOR ANTITHROMBOTIC | SYNTHELABO (FR) | 1998-01-27 | — | — | US | disclosed |