Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299691 | 0.88 | RAB9A (0.44) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8297766 | 0.86 | RAB9A (0.41) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8297858 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL8301789 | 0.79 | NR5A1 (0.36) | KDM4EALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL9814407 | 0.77 | L3MBTL1 (0.63) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9618529 | 0.76 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9074735 | 0.76 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9450010 | 0.76 | KDM4E (0.74) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL9181458 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1HPGDL3MBTL1HTT | |
| SCHEMBL13402231 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1HPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825987-B1 | 1-FLUORISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0825987-A1 | 1-FLUORISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996035674-A1 | 1-FLUORISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |