Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265834 | 0.83 | MEN1 (0.45) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL19255040 | 0.79 | KMT2A (0.48) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5750687 | 0.77 | KMT2A (0.49) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7677787 | 0.76 | SMN1; SMN2 (0.45) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1716137 | 0.75 | ALDH1A1 (0.43) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11729721 | 0.74 | KMT2A (0.46) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6986834 | 0.74 | NLRP3 (0.44) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL30503600 | 0.73 | GPR35 (0.44) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2594851 | 0.73 | GPR35 (0.44) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2592052 | 0.68 | CYP3A4 (0.44) | KMT2AMEN1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000838-A1 | 4-(AMINOMETHYL)-PIPERIDINE BENZAMIDES AS 5HT4-ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-06 | — | — | WO | disclosed |