Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 7/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444415 | 0.79 | ALPL (0.73) | ALPLCA12CA9MAPTTP53 | |
| SCHEMBL2846632 | 0.76 | ALPL (0.73) | ALPLCA12MAPTTP53ALDH1A1 | |
| SCHEMBL4638840 | 0.76 | ALPL (0.73) | ALPLCA12TP53ACRPLA2G10 | |
| SCHEMBL18726258 | 0.76 | ACR (0.57) | ALPLCA12CA9MAPTTP53 | |
| SCHEMBL2789578 | 0.76 | TP53 (0.74) | ALPLCA12MAPTGAATP53 | |
| SCHEMBL2848443 | 0.75 | ALPL (0.76) | ALPLCA9MAPTGAATP53 | |
| SCHEMBL27313254 | 0.74 | ALPL (0.50) | ALPLCA12CA9MAPTGAA | |
| SCHEMBL4789868 | 0.74 | CCNC (0.54) | ALPLCA12MAPTGAATP53 | |
| SCHEMBL15651990 | 0.74 | PLA2G10 (0.41) | ALPLMAPTGAATP53RAB9A | |
| SCHEMBL2845103 | 0.72 | PLA2G10 (0.52) | ALPLCA12CA9MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037779-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |