Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 9/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488692 | 0.84 | L3MBTL1 (0.49) | LIPEPIK3CDL3MBTL1CCNA2CDK2 | |
| SCHEMBL5375657 | 0.84 | DPP4 (0.40) | LIPEACHEF10CCNA2CDK2 | |
| SCHEMBL5720951 | 0.84 | DPP4 (0.40) | LIPEACHEF10CCNA2CDK2 | |
| SCHEMBL5375589 | 0.84 | DPP4 (0.40) | LIPEACHEF10CCNA2CDK2 | |
| SCHEMBL6783378 | 0.78 | LMNA (0.50) | CCNA2CDK2CCNA1 | |
| SCHEMBL5936077 | 0.78 | FPR2 (0.44) | F10CCNA2CDK2CCNA1 | |
| SCHEMBL12528001 | 0.76 | HTT (0.48) | — | |
| SCHEMBL5377448 | 0.75 | HDAC8 (0.40) | LIPECCNA2CDK2CCNA1 | |
| SCHEMBL25269677 | 0.74 | HDAC6 (0.46) | — | |
| SCHEMBL25868401 | 0.74 | ROCK2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110997-A1 | 3- SULFONYLAMINO- PYRROLIDINE- 2- ONE DERIVATIVES AS INHIBITORS OF FACTOR XA | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |