Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296404 | 0.94 | DRD4 (0.60) | DRD4SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8297268 | 0.80 | DRD4 (0.56) | DRD4SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8298230 | 0.80 | HTT (0.57) | DRD4SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8304327 | 0.80 | F10 (0.39) | DRD4LMNAHTTALDH1A1KDM4E | |
| SCHEMBL17731134 | 0.78 | DRD4 (0.67) | DRD4SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8300501 | 0.77 | DRD4 (0.60) | DRD4SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8296828 | 0.76 | DRD2 (0.56) | SMN1; SMN2LMNAHTTDRD2SLC6A4 | |
| SCHEMBL8297273 | 0.76 | HTR1D (0.62) | DRD2 | |
| SCHEMBL4005976 | 0.76 | DRD4 (0.55) | DRD4SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8230021 | 0.75 | ALDH1A1 (0.63) | DRD4SMN1; SMN2LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |