Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299569 | 0.80 | DRD4 (0.56) | ALDH1A1LMNAKDM4EKMT2ADRD2 | |
| SCHEMBL8296404 | 0.76 | DRD4 (0.60) | ALDH1A1LMNAKDM4EDRD2SLC6A4 | |
| SCHEMBL12386856 | 0.67 | SLC6A4 (0.56) | KDM4EKMT2ADRD2SLC6A4HRH3 | |
| SCHEMBL9674195 | 0.66 | ADRA1A (0.58) | ALDH1A1MAPTKDM4EHSD17B10DRD2 | |
| Hydrochloric Acid SCHEMBL9323862 | 0.65 | ADRA1A (0.57) | ALDH1A1MAPTKDM4EHSD17B10DRD2 | |
| SCHEMBL30881666 | 0.65 | LMNA (0.52) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL29209685 | 0.65 | LMNA (0.52) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL28805535 | 0.65 | HRH3 (0.56) | ALDH1A1KDM4EKMT2ADRD2SLC6A4 | |
| SCHEMBL12000672 | 0.64 | DRD2 (0.49) | DRD2SLC6A4GAAHRH3 | |
| SCHEMBL9324793 | 0.64 | DRD2 (0.51) | LMNAPKMKMT2ADRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |