Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593268 | 0.80 | SLC6A3 (0.38) | MEN1KMT2ASLC6A3SIGMAR1CYP1A2 | |
| SCHEMBL8590301 | 0.79 | SLC6A3 (0.37) | MEN1KMT2ASLC6A3SIGMAR1CYP1A2 | |
| SCHEMBL8290867 | 0.79 | MEN1 (0.39) | MEN1KMT2ASLC6A3KCNA5SCN5A | |
| SCHEMBL8556420 | 0.78 | MEN1 (0.41) | MEN1KMT2ASLC6A3KCNA5SCN5A | |
| SCHEMBL8592295 | 0.75 | MEN1 (0.38) | MEN1KMT2ASLC6A3SIGMAR1CYP1A2 | |
| SCHEMBL8703966 | 0.73 | MEN1 (0.43) | MEN1KMT2ASLC6A3KCNA5SCN5A | |
| SCHEMBL4631262 | 0.72 | SLC6A3 (0.43) | MEN1KMT2ASLC6A3KCNA5SCN5A | |
| SCHEMBL7847786 | 0.71 | MEN1 (0.42) | MEN1KMT2ASLC6A3KCNA5SCN5A | |
| SCHEMBL5858037 | 0.70 | MEN1 (0.45) | MEN1KMT2ACHEK1MAPT | |
| SCHEMBL13316560 | 0.70 | MEN1 (0.45) | MEN1KMT2ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512901-B1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-06-23 | — | — | EP | disclosed |
| EP-0512901-A1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-11-11 | — | — | EP | disclosed |