Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298648 | 0.87 | CDK9 (0.36) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8302338 | 0.86 | ITGB3 (0.42) | ALDH1A1ITGB3ITGA2BHTR2AHRH1 | |
| SCHEMBL8301327 | 0.82 | KDM4E (0.43) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8300030 | 0.81 | KDM4E (0.45) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8613755 | 0.81 | ITGB3 (0.56) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8298652 | 0.80 | ITGB3 (0.45) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8300507 | 0.79 | KDM4E (0.43) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8304879 | 0.78 | KDM4E (0.42) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8305336 | 0.78 | KDM4E (0.43) | KDM4EMEN1ALDH1A1KMT2AITGB3 | |
| SCHEMBL8300686 | 0.77 | NAMPT (0.43) | KDM4EMEN1ALDH1A1KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808306-B1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |