Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6647861 | 0.80 | LOXL2 (0.46) | PLAUF2PRSS1MAPTALDH1A1 | |
| SCHEMBL20118384 | 0.75 | SLC1A3 (0.44) | MAOAPRSS1RAB9AMEN1KMT2A | |
| SCHEMBL8180792 | 0.74 | RAB9A (0.51) | MAOARAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL2257827 | 0.71 | F2 (0.42) | F2PRSS1PRSS3MEN1KMT2A | |
| SCHEMBL3862551 | 0.71 | MASP2 (0.46) | MAOAMASP2PLAUTHPOF2 | |
| SCHEMBL6960874 | 0.69 | MEN1 (0.55) | MAOAMASP2PLAUTHPOF2 | |
| SCHEMBL7307963 | 0.69 | KMT2A (0.50) | APEX1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL26482808 | 0.69 | CYP1A2 (0.47) | MAOAF2RAB9AMEN1KMT2A | |
| SCHEMBL26482519 | 0.69 | PLAU (0.41) | MASP2PLAUTHPOF2PRSS1 | |
| SCHEMBL4619841 | 0.69 | PLAU (0.54) | MASP2PLAUTHPOF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113278-A2 | ACYLSULFAMIDE INHIBITORS OF FACTOR VIIA | GENENTECH, INC. (US) | 2004-12-29 | — | — | WO | disclosed |