Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.58 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.58 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.58 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612688 | 0.95 | NAAA (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL19612671 | 0.93 | NAAA (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL3252805 | 0.89 | PLAAT3 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL27472305 | 0.87 | PLAAT3 (0.60) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL5024832 | 0.86 | SMN1; SMN2 (0.68) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL3891167 | 0.84 | PLAAT3 (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL8170713 | 0.81 | NAAA (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL7829175 | 0.81 | SMN1; SMN2 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4HTR3E | |
| SCHEMBL11701911 | 0.81 | TAAR1 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL8084064 | 0.81 | TAAR1 (0.50) | SMN1; SMN2TAAR1NAAACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478195-B1 | Dihydropyridazinones and pyridazinones as fungicides | ROHM & HAAS (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5753642-A | AGRICULTURE, MEDICINE | ROHM AND HAAS COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5728715-A | FOR MAMMALS, AGRICULTURE, RICE, WHEAT, TOMATOES | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728698-A | AGRICULTURAL USE, RICE, WHEAT | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728694-A | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5726162-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5726176-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5631254-A | RICE; HUMAN INFECTIONS | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5552409-A | PHYTOPATHOGENIC, RICE | ROHM AND HAAS COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0478195-A1 | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-01 | — | — | EP | disclosed |