Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612566 | 0.93 | NAAA (0.55) | TAAR1NAAASLC6A3DRD2SLC6A4 | |
| SCHEMBL1447034 | 0.89 | TAAR1 (0.53) | TAAR1NAAASLC6A3CNR1FFAR1 | |
| SCHEMBL315728 | 0.84 | SLC6A3 (0.63) | TAAR1NAAASLC6A3DRD2SLC6A4 | |
| SCHEMBL2090292 | 0.84 | TAAR1 (0.56) | TAAR1NAAASLC6A3DRD2SLC6A4 | |
| SCHEMBL10110719 | 0.83 | TAAR1 (0.50) | TAAR1NAAASLC6A3DRD2SLC6A4 | |
| SCHEMBL8301337 | 0.81 | PLAAT3 (0.58) | TAAR1NAAACNR1SMN1; SMN2 | |
| SCHEMBL2813238 | 0.81 | TAAR1 (0.49) | TAAR1NAAASLC6A3CNR1FFAR1 | |
| SCHEMBL11701911 | 0.79 | TAAR1 (0.50) | TAAR1SLC6A3CNR1FFAR1NR3C2 | |
| SCHEMBL1205707 | 0.79 | MAPT (0.62) | TAAR1NAAASLC6A3FFAR1HDAC3 | |
| SCHEMBL28229641 | 0.79 | FFAR1 (0.51) | TAAR1NAAASLC6A3DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159287-C | Anticonvulsant and sentral nervous system-active bis (fluorophenyl) alkylamides | NPSҩ������˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1284056-A | Anticonvulsant and sentral nervous system-active bis (fluorophenyl) alkylamides | NPS PHARMA INC (US) | 2001-02-14 | — | — | CN | disclosed |
| EP-1042275-A1 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999029657-A1 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 1999-06-17 | — | — | WO | disclosed |