Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301665 | 0.87 | NPC1 (0.52) | GAALMNAHPGD | |
| SCHEMBL8292287 | 0.84 | GAA (0.57) | NLRP3GAALMNAHPGD | |
| SCHEMBL8299247 | 0.82 | PDE5A (0.53) | GAALMNAHPGD | |
| SCHEMBL6944281 | 0.82 | GAA (0.55) | GAALMNAHPGD | |
| SCHEMBL8299255 | 0.79 | PDE5A (0.53) | GAALMNAHPGD | |
| SCHEMBL8416857 | 0.79 | NLRP3 (0.45) | NLRP3GAALMNAHPGDCYP1A2 | |
| SCHEMBL8416853 | 0.79 | NLRP3 (0.45) | NLRP3GAALMNAHPGDCYP1A2 | |
| SCHEMBL8297189 | 0.78 | GAA (0.55) | GAALMNAHPGDCYP1A2CYP2D6 | |
| SCHEMBL17241767 | 0.77 | GAA (0.57) | NLRP3GAALMNAHPGD | |
| SCHEMBL8602155 | 0.76 | POLB (0.49) | NLRP3LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| CN-1118595-A | Anthranilic acid derivative | EISAI CO LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |