Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300888 | 0.87 | POLB (0.64) | POLBGAAEPHX2MCHR1MAPT | |
| SCHEMBL8299249 | 0.78 | POLB (0.61) | POLBGAAMCHR1MAPTKDM4E | |
| SCHEMBL8436830 | 0.77 | GAA (0.54) | POLBGAAKDM4EALDH1A1PDE4A | |
| SCHEMBL8297193 | 0.76 | POLB (0.58) | POLBGAARAB9ANPC1F10 | |
| SCHEMBL8297238 | 0.74 | POLB (0.53) | POLBGAAMCHR1MAPTKDM4E | |
| SCHEMBL9225103 | 0.74 | EPHX2 (0.55) | RAB9AEPHX2F10MAPTKDM4E | |
| SCHEMBL8414604 | 0.73 | LMNA (0.46) | POLBGAAMAPTLMNA | |
| SCHEMBL17241507 | 0.73 | RAB9A (0.55) | POLBRAB9ANPC1MAPTKDM4E | |
| SCHEMBL8293460 | 0.72 | MAPT (0.52) | POLBGAAMAPTLMNAMAPK1 | |
| SCHEMBL8570087 | 0.72 | GAA (0.57) | POLBGAAMCHR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |