Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297950 | 0.79 | MEN1 (0.46) | GSK3BADKMEN1KMT2AKDM4E | |
| SCHEMBL10432295 | 0.78 | ALDH1A1 (0.39) | KDM4EALDH1A1TDP1HTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27450739 | 0.78 | MEN1 (0.44) | GSK3BADKMEN1KMT2AKDM4E | |
| SCHEMBL3391817 | 0.75 | CDC7 (0.42) | GSK3BADKMEN1KMT2AKDM4E | |
| SCHEMBL2291368 | 0.74 | ALDH1A1 (0.49) | GSK3BADKMEN1KMT2AKDM4E | |
| SCHEMBL1156690 | 0.73 | ALDH1A1 (0.47) | GSK3BADKMEN1KMT2AKDM4E | |
| Bicarbonate SCHEMBL11569280 | 0.73 | NR4A1 (0.58) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL11745392 | 0.73 | DHFR (0.46) | GSK3BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6929782 | 0.72 | MEN1 (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| Bicarbonate SCHEMBL27535643 | 0.71 | NR4A1 (0.56) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647629-B1 | Neurotensin active substituted 1-naphthylpyrazole-3-carboxamides, their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-07-07 | — | — | EP | claimed |