Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301543 | 1.00 | TDP1 (0.37) | TDP1ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL8302038 | 0.84 | MIF (0.35) | GAAFAAHNPC1RAB9AMEN1 | |
| SCHEMBL8302035 | 0.84 | MIF (0.35) | GAAFAAHNPC1RAB9AMEN1 | |
| SCHEMBL8302198 | 0.82 | ALDH1A1 (0.36) | TDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8302197 | 0.82 | ALDH1A1 (0.36) | TDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8305288 | 0.73 | PLK1 (0.49) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8305287 | 0.73 | PLK1 (0.49) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8307303 | 0.72 | — | — | |
| SCHEMBL8307299 | 0.72 | — | — | |
| SCHEMBL8304607 | 0.71 | GPR55 (0.42) | TDP1ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948485-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | claimed |
| WO-1998028278-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | claimed |