Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305287 | 1.00 | PLK1 (0.49) | PLK1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27884935 | 0.77 | PLA2G7 (0.63) | PLK1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8302198 | 0.76 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL8302197 | 0.76 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL8302038 | 0.75 | MIF (0.35) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8302035 | 0.75 | MIF (0.35) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8301543 | 0.73 | TDP1 (0.37) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8301545 | 0.73 | TDP1 (0.37) | RAB9ANPC1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28667339 | 0.69 | NPC1 (0.60) | PLK1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28702214 | 0.68 | RAB9A (0.58) | PLK1RAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948485-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | claimed |
| WO-1998028278-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | claimed |