SCHEMBL8304607

SCHEMBL8304607

O=C(O)CON=Cc1cc[nH]n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.42
ALOX15 P16050 1/20 0.35
ATM Q13315 1/20 0.35
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
OGFRL1 Q5TC84 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK8 P45983 1/20 0.33
MAPK9 P45984 1/20 0.33
MAPK10 P53779 1/20 0.33
CCNO P22674 1/20 0.32
LMNA P02545 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8304605 1.00 GPR55 (0.42) GPR55ALOX15ATMOPRM1OPRD1
SCHEMBL8307891 0.80 USP2 (0.40) SMN1; SMN2MEN1KMT2AKDM4EALDH1A1
SCHEMBL8307890 0.80 USP2 (0.40) SMN1; SMN2MEN1KMT2AKDM4EALDH1A1
SCHEMBL8302197 0.75 ALDH1A1 (0.36) SMN1; SMN2KDM4EALDH1A1LMNAPOLB
SCHEMBL8302038 0.73 MIF (0.35) ALOX15SMN1; SMN2MEN1KMT2AKDM4E
SCHEMBL8613027 0.72 ATM (0.59) GPR55ALOX15ATMSMN1; SMN2MEN1
SCHEMBL8291064 0.72 ATM (0.59) GPR55ALOX15ATMSMN1; SMN2MEN1
SCHEMBL8301543 0.71 TDP1 (0.37) SMN1; SMN2MEN1KMT2AALDH1A1NPC1
SCHEMBL8301545 0.71 TDP1 (0.37) SMN1; SMN2MEN1KMT2AALDH1A1NPC1
SCHEMBL8303405 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948485-A1 PESTICIDAL 1-ARYLPYRAZOLES RHONE-POULENC AGROCHIMIE (FR) 1999-10-13 EP claimed
WO-1998028278-A1 PESTICIDAL 1-ARYLPYRAZOLES RHONE-POULENC AGROCHIMIE (FR) 1998-07-02 WO claimed