Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13206126 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3366196 | 0.85 | SIRT6 (0.57) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7415910 | 0.82 | JAK2 (0.48) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL19260129 | 0.82 | MAPT (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL27870573 | 0.79 | TSHR (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL25218344 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4137682 | 0.79 | HPGD (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5333636 | 0.79 | LMNA (0.52) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL31277054 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8296716 | 0.77 | IP6K1 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| CN-1118595-A | Anthranilic acid derivative | EISAI CO LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5039329-A | Plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1991-08-13 | — | — | US | disclosed |
| US-4946492-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |