Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751469 | 0.87 | DPP4 (0.38) | DPP4DPP7MMEL1ITGB3ITGB1 | |
| SCHEMBL6697319 | 0.80 | DPP4 (0.39) | DPP4DPP7MMEL1 | |
| SCHEMBL10054446 | 0.73 | MMEL1 (0.42) | DPP4DPP7MMEL1DPP8 | |
| SCHEMBL2364410 | 0.73 | CTSS (0.45) | DPP4DPP7MMEL1DPP8 | |
| SCHEMBL10054447 | 0.73 | CTSS (0.45) | DPP4DPP7MMEL1DPP8 | |
| SCHEMBL1509219 | 0.73 | CTSS (0.45) | DPP4DPP7MMEL1DPP8 | |
| SCHEMBL14687291 | 0.71 | ALDH1A1 (0.43) | DPP4DPP7 | |
| SCHEMBL8231920 | 0.71 | DPP4 (0.45) | DPP4DPP7DPP8 | |
| SCHEMBL13825142 | 0.71 | MMEL1 (0.41) | DPP4MMEL1ITGB3 | |
| SCHEMBL6692860 | 0.70 | DPP4 (0.43) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087650-A2 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BETA-AMINO ACID AMIDE DIPEPTIDYL PEPTIDASE-IV INHIBITORS | MERCK & CO. INC. (US) | 2004-10-14 | — | — | WO | disclosed |