Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300403 | 0.92 | HTT (0.67) | CASP6HTTKMT2ALMNAMAPT | |
| SCHEMBL8299130 | 0.79 | CASP6 (0.51) | CASP6HTTKMT2ALMNAMAPT | |
| SCHEMBL3364018 | 0.71 | MAPT (0.62) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL3364021 | 0.71 | MAPT (0.62) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL3366536 | 0.69 | OXTR (0.74) | KMT2ALMNAMAPTHPGDCYP3A4 | |
| SCHEMBL3369096 | 0.69 | OXTR (0.74) | KMT2ALMNAMAPTHPGDCYP3A4 | |
| SCHEMBL18958907 | 0.68 | PKM (0.70) | HTTKMT2ALMNAMAPTHPGD | |
| SCHEMBL21033437 | 0.66 | PKM (0.67) | HTTKMT2ALMNAMAPTHPGD | |
| SCHEMBL16557461 | 0.65 | HPGD (0.69) | KMT2ALMNAMAPTHPGDPKM | |
| SCHEMBL18958914 | 0.65 | PKM (0.68) | HTTLMNAMAPTHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037779-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |