Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300403 | 0.81 | HTT (0.67) | CASP6HTTKMT2AMAPTLMNA | |
| SCHEMBL8302596 | 0.79 | CASP6 (0.60) | CASP6HTTKMT2ATRPM5MAPT | |
| SCHEMBL7961337 | 0.66 | TRPM5 (0.59) | TRPM5HPGDALDH1A1GAA | |
| SCHEMBL12793829 | 0.66 | ALDH1A1 (0.66) | KMT2ATRPM5MAPTLMNAGLA | |
| SCHEMBL1225432 | 0.62 | TRPM5 (1.00) | HTTTRPM5MAPTLMNAHPGD | |
| SCHEMBL1225431 | 0.62 | TRPM5 (1.00) | HTTTRPM5MAPTLMNAHPGD | |
| SCHEMBL7971480 | 0.62 | GAA (0.66) | TRPM5MAPTLMNAHPGDGAA | |
| SCHEMBL10447688 | 0.62 | LMNA (0.65) | HTTKMT2AMAPTLMNAGLA | |
| SCHEMBL1224628 | 0.61 | TRPM5 (1.00) | HTTKMT2ATRPM5MAPTLMNA | |
| SCHEMBL1224631 | 0.61 | TRPM5 (1.00) | HTTKMT2ATRPM5MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037779-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |