Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | FADS1 | O60427 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921278 | 0.82 | KDM4E (0.60) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL297624 | 0.80 | KDM4E (0.59) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL112991 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL29463616 | 0.80 | KDM4E (0.59) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL375579 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL16677840 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL15140837 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL5668549 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRKDM4EFADS1 | |
| SCHEMBL31267447 | 0.77 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL5574637 | 0.77 | FADS1 (0.54) | ALDH1A1HSD17B10CFTRKDM4EFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009392-A2 | DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-03 | — | — | WO | disclosed |