Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28193055 | 0.84 | ALDH1A1 (0.48) | FADS1ALDH1A1HSD17B10CFTRPTGS1 | |
| SCHEMBL8634908 | 0.84 | RAB9A (0.50) | FADS1ALDH1A1HSD17B10CFTRPTGS1 | |
| SCHEMBL30385607 | 0.83 | KDM4E (0.55) | FADS1ALDH1A1HSD17B10CFTRPTGS1 | |
| SCHEMBL6999516 | 0.82 | ALDH1A1 (0.55) | FADS1ALDH1A1HSD17B10CFTRPTGS1 | |
| SCHEMBL7160814 | 0.81 | CYP3A4 (0.53) | ALDH1A1KDM4ENPC1GAAMAPT | |
| SCHEMBL9921278 | 0.80 | KDM4E (0.60) | FADS1ALDH1A1HSD17B10CFTRPTGS1 | |
| SCHEMBL5807531 | 0.80 | MAPT (0.60) | FADS1ALDH1A1HSD17B10CFTRPTGS1 | |
| SCHEMBL11589554 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4ENPC1MAPTHPGD | |
| SCHEMBL11743614 | 0.79 | NPC1 (0.72) | FADS1ALDH1A1HSD17B10CFTRPTGS1 | |
| SCHEMBL17744848 | 0.79 | PTGS1 (0.75) | FADS1ALDH1A1HSD17B10PTGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2007-01-04 | — | — | US | disclosed |
| EP-1634079-A1 | SCREENING METHOD FOR SUBSTANCES BINDING TO MEROZOITE SURFACE PROTEIN-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004113920-A1 | SCREENING METHOD FOR SUBSTANCES BINDING TO MEROZOITE SURFACE PROTEIN-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | CD2BP2, MASP2, CD14 | FADS1 4798/4885ALDH1A1 3620/4885HSD17B10 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.