SCHEMBL830351

SCHEMBL830351

CC(C)c1ccc2c(N)c(C(C)C)ccc2c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.35
LMNA P02545 2/20 0.35
SLC6A2 P23975 2/20 0.35
HTR2B P41595 2/20 0.35
GABRB2 P47870 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
FAAH O00519 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
GABRB1 P18505 1/20 0.35
PTGS1 P23219 1/20 0.35
HTR2C P28335 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9879909 0.85 GABRA1 (0.39) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL4656983 0.85 ALDH1A1 (0.52) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL28883484 0.82 NR4A2 (0.48) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL23479388 0.77 ALDH1A1 (0.44) CYP1A2CYP3A4HPGDTSHRHTR2C
SCHEMBL19998489 0.76 LMNA (0.38) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL104314 0.74 GABRA1 (0.55) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL19972055 0.74 LMNA (0.32) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL6542243 0.74 POLB (0.42) GABRA1LMNASLC6A2HTR2BGABRB2
SCHEMBL19972025 0.74 GABRA1 (0.54) GABRA1LMNASLC6A2HTR2BGABRB2
Hydrochloric Acid SCHEMBL8615487 0.72 GABRA1 (0.52) GABRA1LMNASLC6A2HTR2BGABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059672-A Polyurea coatings; high tensile strength, chemical and corrosion resistant THARE COAT, INC. (US) 1991-10-22 US claimed
EP-3144728-B1 TONER BINDER, AND TONER SANYO CHEMICAL IND LTD (JP) 2021-04-21 EP disclosed
US-20210002441-A1 RESIN PARTICLES AND METHOD FOR PRODUCING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-07 US disclosed
CN-111240165-A Toner binder and toner 三洋化成工业株式会社 2020-06-05 CN disclosed
CN-106462094-B Toner binder and toner 三洋化成工业株式会社 2020-05-01 CN disclosed
US-10114304-B2 Toner binder, and toner SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-30 US disclosed
US-10007207-B2 Liquid developer and method for manufacturing the same Konica Minolta, Inc. (JP) 2018-06-26 US disclosed
US-20180164708-A1 TONER BINDER, AND TONER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2018-06-14 US disclosed
US-9921505-B2 Toner binder, and toner SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-20 US disclosed
EP-3026492-B1 TONER BINDER AND TONER SANYO CHEMICAL IND LTD (JP) 2018-01-10 EP disclosed
EP-0219709-B1 POLYMETHYLENE POLYPHENYLAMINE MODIFIED DIAMINE CHAIN EXTENDERS AND POLYUREA ELASTOMERS THEREFROM THE DOW CHEMICAL COMPANY (US) 1989-11-23 EP disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
EP-0219709-A2 Polymethylene polyphenylamine modified diamine chain extenders and polyurea elastomers therefrom THE DOW CHEMICAL COMPANY (US) 1987-04-29 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
EP-0075130-B1 IMPROVED REACTION INJECTION MOLDING PROCESS THE DOW CHEMICAL COMPANY (US) 1986-09-17 EP disclosed
EP-0185369-A2 Polyamide-polyurea polymers THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP disclosed
US-4552945-A REACTION INJECTION MOLDING, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP disclosed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US disclosed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US disclosed