Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303317 | 0.95 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8298238 | 0.91 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8303384 | 0.86 | HTR1A (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8298953 | 0.86 | HTR1A (0.50) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8297151 | 0.83 | SLC6A4 (0.48) | SLC6A4CYP2D6 | |
| SCHEMBL8299474 | 0.81 | KCNH2 (0.51) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8572323 | 0.81 | HTR1D (0.49) | — | |
| SCHEMBL8296789 | 0.81 | HTR1A (0.62) | SLC6A4 | |
| SCHEMBL8304106 | 0.79 | DRD4 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8302931 | 0.79 | OPRM1 (0.56) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |