Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5869086 | 0.89 | MIF (0.43) | GAANPSR1MAP2K1KMT2AMEN1 | |
| SCHEMBL7887305 | 0.86 | MIF (0.40) | GAANPSR1MAP2K1KMT2AMEN1 | |
| SCHEMBL1823015 | 0.86 | MIF (0.44) | GAANPSR1MAP2K1KMT2AMEN1 | |
| SCHEMBL4178450 | 0.84 | CA12 (0.47) | GAANPSR1MAP2K1KMT2AMEN1 | |
| SCHEMBL7889566 | 0.82 | GABRA1 (0.43) | GAANPSR1KMT2AMEN1MIF | |
| SCHEMBL2080446 | 0.81 | CES2 (0.49) | GAANPSR1KMT2AMEN1MIF | |
| SCHEMBL12692656 | 0.81 | NLRP3 (0.44) | GAANPSR1KMT2AMEN1MIF | |
| SCHEMBL406494 | 0.81 | GAA (0.49) | GAANPSR1MAP2K1KMT2AMEN1 | |
| SCHEMBL13537990 | 0.79 | MIF (0.42) | GAANPSR1KMT2AMEN1MIF | |
| SCHEMBL1568667 | 0.79 | DGAT1 (0.49) | GAANPSR1MAP2K1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906285-A1 | 3-CYANOARYL PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER AG (DE) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997046535-A1 | 3-CYANOARYL PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-11 | — | — | WO | disclosed |
| WO-1996001255-A1 | 3-(CYANOPHENYL)-PYRAZOLE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 1996-01-18 | — | — | WO | disclosed |