Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591838 | 0.89 | ALDH1A1 (0.47) | NPC1MEN1KMT2AGSK3BRAB9A | |
| SCHEMBL8552521 | 0.78 | NPC1 (0.45) | SMPD1NPC1MEN1KMT2ACYP3A4 | |
| SCHEMBL8308343 | 0.77 | TLR4 (0.58) | TNKS2PARP2CYP3A4CTSVCTSL | |
| SCHEMBL7405256 | 0.77 | PPARD (0.48) | SMPD1NPC1MEN1KMT2ATNKS2 | |
| SCHEMBL8304336 | 0.76 | MAOB (0.51) | SMPD1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL8591834 | 0.75 | NMT1 (0.45) | SMPD1NPC1MEN1KMT2ATNKS2 | |
| SCHEMBL8305123 | 0.74 | HTR3A (0.54) | NPC1MEN1KMT2AGSK3BRAB9A | |
| SCHEMBL8546942 | 0.71 | SMPD1 (0.46) | SMPD1NPC1CYP3A4RAB9ASMN1; SMN2 | |
| SCHEMBL1942609 | 0.70 | HRH3 (0.44) | KMT2ATNKS2PARP2CYP3A4CTSV | |
| SCHEMBL26967747 | 0.70 | F2 (0.50) | MEN1KMT2ARAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835254-B1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1999-09-01 | — | — | EP | disclosed |
| EP-0835254-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1998-04-15 | — | — | EP | disclosed |
| WO-1996038444-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1996-12-05 | — | — | WO | disclosed |