Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303707 | 0.78 | SMPD1 (0.45) | NPC1MEN1KMT2ACYP3A4RAB9A | |
| SCHEMBL8546942 | 0.76 | SMPD1 (0.46) | NPC1CYP3A4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7405256 | 0.72 | PPARD (0.48) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL15876017 | 0.71 | NPC1 (0.56) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8304336 | 0.71 | MAOB (0.51) | NPC1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL8591838 | 0.71 | ALDH1A1 (0.47) | NPC1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL28021758 | 0.70 | HDAC6 (0.58) | NPC1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL5795231 | 0.70 | MAPT (0.46) | NPC1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL26697665 | 0.70 | MEN1 (0.59) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL4666205 | 0.70 | RAB9A (0.74) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835254-A1 | OXAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTICAL USE | SYNTHELABO (FR) | 1998-04-15 | — | — | EP | disclosed |