Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 9/20 | 0.38 |
| ▸ | CNR1 | P21554 | 10/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309066 | 0.89 | HTR4 (0.46) | GPR55HTR4 | |
| SCHEMBL8306207 | 0.88 | GPR55 (0.35) | GPR55CNR1CNR2HTR4 | |
| SCHEMBL8308257 | 0.86 | NR3C1 (0.39) | GPR55CNR1CNR2HTR4 | |
| SCHEMBL6956244 | 0.84 | FSCN1 (0.33) | GPR55CNR1HTR4 | |
| SCHEMBL7799605 | 0.84 | GPR55 (0.34) | GPR55CNR1HTR4 | |
| SCHEMBL7749150 | 0.83 | MDM2 (0.37) | GPR55CNR1CNR2HTR4 | |
| SCHEMBL7799596 | 0.83 | HTR4 (0.36) | GPR55HTR4 | |
| SCHEMBL8303718 | 0.82 | HTR4 (0.52) | HTR4 | |
| Bromide SCHEMBL8369649 | 0.82 | HTR4 (0.51) | HTR4 | |
| SCHEMBL7810023 | 0.80 | CHRNA7 (0.38) | GPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |