Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976134 | 0.86 | KDM4E (0.48) | KDM4EALOX12CYP3A4TDP1GAA | |
| SCHEMBL6970751 | 0.82 | KDM4E (0.47) | KDM4EALOX12CYP3A4TDP1GAA | |
| SCHEMBL13036181 | 0.77 | KMT2A (0.50) | KDM4ETDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7982959 | 0.76 | MEN1 (0.50) | KDM4EALOX12CYP3A4TDP1MEN1 | |
| SCHEMBL10488788 | 0.74 | KDM4E (0.77) | KDM4EALOX12CYP3A4TDP1GAA | |
| SCHEMBL12180599 | 0.73 | MEN1 (0.50) | KDM4EALOX12CYP3A4TDP1GAA | |
| SCHEMBL812451 | 0.72 | HTT (0.70) | KDM4ECYP3A4TDP1MEN1KMT2A | |
| SCHEMBL10773502 | 0.72 | TSHR (0.50) | TDP1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23714062 | 0.72 | MEN1 (0.45) | KDM4EALOX12CYP3A4TDP1MEN1 | |
| SCHEMBL11912045 | 0.71 | MEN1 (0.51) | KDM4EALOX12CYP3A4TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929546-A1 | 4-HETAROYLPYRAZOL DERIVATIVES AND THE USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998012192-A1 | 4-HETAROYLPYRAZOL DERIVATIVES AND THE USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |