Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6100315 | 0.82 | L3MBTL1 (0.47) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL5347545 | 0.77 | RAB9A (0.64) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7380970 | 0.75 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2CYP1A2CYP2C19RAB9A | |
| SCHEMBL18218828 | 0.74 | RAB9A (0.55) | L3MBTL1SMN1; SMN2CYP1A2CYP2C19RAB9A | |
| SCHEMBL994563 | 0.73 | RAB9A (0.55) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7057484 | 0.73 | CHRNB2 (0.58) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL3632906 | 0.73 | RAB9A (0.51) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6675218 | 0.72 | TSHR (0.56) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL30395909 | 0.72 | RAB9A (0.50) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL15308192 | 0.72 | TSHR (0.52) | L3MBTL1TSHRSMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835109-A4 | PYRIDINONE-THROMBIN INHIBITORS | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0835109-A1 | PYRIDINONE-THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1998-04-15 | — | — | EP | disclosed |