Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458704 | 0.87 | RAB9A (0.46) | HSD17B10TARBP2RAB9ATSHRLMNA | |
| SCHEMBL8303845 | 0.85 | RXRA (0.41) | TSHRKDM4EMAPTPTGS2ALDH1A1 | |
| SCHEMBL7514117 | 0.85 | SIRT2 (0.34) | TARBP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4442084 | 0.85 | SIRT2 (0.34) | TARBP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4563793 | 0.84 | SIRT2 (0.35) | TARBP2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8305905 | 0.83 | RXRA (0.45) | TSHRKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL4442406 | 0.83 | SIRT2 (0.38) | TARBP2LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7457504 | 0.83 | FAAH (0.43) | HSD17B10TARBP2FAAHRAB9ATSHR | |
| SCHEMBL8303347 | 0.82 | NR4A2 (0.35) | HSD17B10TARBP2LMNAKDM4EMEN1 | |
| SCHEMBL5208950 | 0.82 | HSD17B10 (0.44) | HSD17B10TARBP2FAAHRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036882-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |