Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309374 | 0.94 | MAPT (0.35) | MAPTTP53THRBALDH1A1SMN1; SMN2 | |
| SCHEMBL8303845 | 0.86 | RXRA (0.41) | MAPTALDH1A1KDM4EHTT | |
| SCHEMBL8305905 | 0.81 | RXRA (0.45) | MAPTALDH1A1KDM4EHTT | |
| SCHEMBL4442406 | 0.81 | SIRT2 (0.38) | MAPTALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8303347 | 0.81 | NR4A2 (0.35) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL4563793 | 0.80 | SIRT2 (0.35) | MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8304088 | 0.80 | HSD17B10 (0.40) | MAPTPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL4442084 | 0.80 | SIRT2 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7514117 | 0.80 | SIRT2 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8303146 | 0.79 | CRHR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036882-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |