Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291612 | 0.76 | LMNA (0.52) | DPP4DPP7 | |
| SCHEMBL9873839 | 0.75 | PREP (0.62) | ACEACE2FAPSLC6A1PREP | |
| SCHEMBL9873842 | 0.75 | PREP (0.62) | ACEACE2FAPSLC6A1PREP | |
| SCHEMBL8306791 | 0.73 | MAPT (0.46) | ACEACE2FAPSLC6A1PREP | |
| SCHEMBL7283244 | 0.73 | CYP3A4 (0.48) | DPP4DPP7 | |
| SCHEMBL9569384 | 0.73 | ALDH1A1 (0.47) | — | |
| SCHEMBL7292109 | 0.73 | ALDH1A1 (0.47) | — | |
| SCHEMBL9874002 | 0.70 | PREP (0.49) | ACEFAPSLC6A1PREP | |
| SCHEMBL9874007 | 0.70 | PREP (0.49) | ACEFAPSLC6A1PREP | |
| SCHEMBL7283530 | 0.69 | MEN1 (0.51) | ACEACE2DPP4SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537802-B1 | N-acylpyrrolidines, process for their preparation and their use for prevention and/or treatment of amnesia | ONO PHARMACEUTICAL CO (JP) | 1999-08-25 | — | — | EP | claimed |