Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567787 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTALDH1A1BRD4 | |
| SCHEMBL30576465 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTALDH1A1BRD4 | |
| SCHEMBL431522 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTALDH1A1BRD4 | |
| SCHEMBL8567784 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTALDH1A1BRD4 | |
| SCHEMBL24045426 | 0.82 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL7499391 | 0.79 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1BRD4EPHX2 | |
| SCHEMBL8562039 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BMAPTBRD4EPHX2 | |
| SCHEMBL8562035 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BMAPTBRD4EPHX2 | |
| SCHEMBL8562033 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BMAPTBRD4EPHX2 | |
| SCHEMBL17432673 | 0.76 | HPGD (0.56) | MTNR1AMTNR1BMAPTEPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633261-B1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | YOSHITOMI PHARMACEUTICAL (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5543420-A | ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AGENTS; PREVENTION OF ACCUMULATION OF SORBITOL AND GALACTITOL IN MAMMALIAN TISSUE | THE GREEN CROSS CORPORATION (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0633261-A1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1995-01-11 | — | — | EP | disclosed |