Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575031 | 0.71 | MAOA (0.34) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL767093 | 0.71 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL546688 | 0.71 | MAOA (0.34) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL221025 | 0.71 | CYP1A2 (0.36) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL3235744 | 0.71 | AHR (0.38) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL1002037 | 0.71 | CA12 (0.36) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6863801 | 0.69 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL2958656 | 0.68 | CA1 (0.36) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL10514896 | 0.67 | L3MBTL1 (0.33) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL636934 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685475-B1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1999-01-13 | — | — | EP | claimed |
| US-5622989-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | claimed |
| EP-0685475-A1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | claimed |
| CN-117580569-A | Heterocyclic aldehyde capture compounds and uses thereof | 奥尔德拉医疗公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-115536646-A | Nematicidal active compound and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-103703006-A | Hcv protease inhibitors | SHANGHAI TANGRUN PHARMACEUTICALS CO LTD | 2014-04-02 | — | — | CN | disclosed |
| EP-0685475-B1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1999-01-13 | — | — | EP | disclosed |
| EP-0685475-B1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1999-01-13 | — | — | EP | disclosed |
| US-5622989-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0685475-A1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0685475-A1 | Amino-benzofuryl-and thienyl-derivatives | BAYER AG (DE) | 1995-12-06 | — | — | EP | disclosed |