SCHEMBL2958656

SCHEMBL2958656

[c]1oc2ccccc2c1-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CYP3A4 P08684 3/20 0.36
CA12 O43570 2/20 0.36
TP53 P04637 2/20 0.36
ABCB1 P08183 2/20 0.36
ADORA3 P0DMS8 2/20 0.36
AR P10275 2/20 0.36
CYP1B1 Q16678 2/20 0.36
CA9 Q16790 2/20 0.36
ABCG2 Q9UNQ0 2/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
NPC1 O15118 1/20 0.36
TNKS O95271 1/20 0.36
PARP1 P09874 1/20 0.36
CYP19A1 P11511 1/20 0.36
GABRA1 P14867 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4455299 0.84 GABRP (0.42) SMN1; SMN2GABRPGABRDTNKSPARP1
SCHEMBL21296037 0.84 NOTUM (0.40) CYP3A4TP53CYP1B1HPGDSMN1; SMN2
SCHEMBL21295803 0.80 ALDH1A1 (0.45) CYP3A4TP53HPGDSMN1; SMN2NPC1
SCHEMBL4458452 0.77 ADORA3 (0.46) CA1CA2CYP3A4ADORA3HPGD
SCHEMBL15673590 0.77 CYP2A6 (0.42) CYP3A4MEN1KMT2APDGFRB
SCHEMBL9414866 0.76 ESR1 (0.57) CYP3A4HPGDCYP19A1MEN1KMT2A
SCHEMBL9624356 0.75 ABCB1 (0.51) CA1CA2CYP3A4TP53ABCB1
SCHEMBL5567669 0.74 KDM4E (0.36) TP53HPGDSMN1; SMN2NPC1CYP19A1
SCHEMBL5324075 0.72 NPC1 (0.50) TP53HPGDSMN1; SMN2NPC1RAB9A
SCHEMBL7972358 0.72 CYP2A6 (0.38) CA12TP53CA9HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117767-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-06 WO claimed
CN-114402451-A Photoelectric conversion element and imaging element 索尼集团公司 2022-04-26 CN claimed
CN-110739406-B Organic electroluminescent device 乐金显示有限公司 2022-04-19 CN claimed
CN-110739406-A Organic electroluminescent device 乐金显示有限公司 2020-01-31 CN claimed
EP-1628970-A2 HETEROCYCLE SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B The Institutes of Pharmaceutical Discovery, LLC (US) 2006-03-01 EP claimed
US-6849629-B2 Heteroaromatic substituted sulfonyl or sulfoxide or thio-pyridazinone derivatives, useful for treating diabetic complications and cardiovascular disorders PFIZER, INC. (US) 2005-02-01 US claimed
EP-1373259-B1 PYRIDAZINONE ALDOSE REDUCTASE INHIBITORS PFIZER PROD INC (US) 2004-12-29 EP claimed
WO-2004099192-A2 HETEROCYCLE SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B THE INSTITUTES OF PHARMACEUTICAL DISCOVERY, LLC (US) 2004-11-18 WO claimed
US-20030162784-A1 Pyridazinone aldose reductase inhibitors MYLARI BANAVARA L (US) 2003-08-28 US claimed
US-20020143017-A1 Pyridazinone aldose reductase inhibitors MYLARI BANAVARA L (US) 2002-10-03 US claimed
EP-0659193-B1 PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 1997-12-10 EP claimed
CN-113727980-B Compound and organic light emitting device comprising the same 株式会社LG化学 2024-06-28 CN disclosed
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2024-06-25 US disclosed
WO-2024117767-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-06 WO disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
US-20020143017-A1 Pyridazinone aldose reductase inhibitors MYLARI BANAVARA L (US) 2002-10-03 US disclosed
EP-0659193-B1 PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 1997-12-10 EP disclosed
EP-0659193-A1 PLATELET AGGREGATION INHIBITORS G.D. Searle & Co. (US) 1995-06-28 EP disclosed
US-5354738-A Amino acid derivatives G. D. SEARLE & CO. (US) 1994-10-11 US disclosed
WO-1994005694-A1 PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes FDFT1, SUN2, CDC73 CA1 4332/4885CA2 3904/4885CYP3A4 1502/4885
US-20030162784-A1 Pyridazinone aldose reductase inhibitors SLC5A1, ALDOA, AKR1B1 CA1 3476/4885CA2 782/4885CYP3A4 1647/4885
US-20020143017-A1 Pyridazinone aldose reductase inhibitors SLC5A1, AKR1B1, AKR1D1 CA1 3972/4885CA2 1112/4885CYP3A4 1869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.