Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304463 | 1.00 | MAPT (0.48) | MAPTHTTGAALMNATDP1 | |
| SCHEMBL24485236 | 0.85 | ALDH1A1 (0.46) | MAPTHTTGAALMNAL3MBTL1 | |
| SCHEMBL29453685 | 0.85 | ALDH1A1 (0.46) | MAPTHTTGAALMNAL3MBTL1 | |
| SCHEMBL22719323 | 0.84 | ALDH1A1 (0.57) | MAPTHTTGAALMNATDP1 | |
| SCHEMBL22719324 | 0.84 | ALDH1A1 (0.57) | MAPTHTTGAALMNATDP1 | |
| SCHEMBL19907918 | 0.81 | TDP1 (0.45) | MAPTLMNATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL1955351 | 0.79 | RECQL (0.54) | MAPTHTTGAALMNATDP1 | |
| SCHEMBL1955354 | 0.79 | RECQL (0.54) | MAPTHTTGAALMNATDP1 | |
| SCHEMBL69990 | 0.78 | L3MBTL1 (0.62) | MAPTHTTLMNATDP1L3MBTL1 | |
| SCHEMBL29416324 | 0.78 | L3MBTL1 (0.62) | MAPTHTTLMNATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739341-B1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | NOVARTIS AG (CH) | 1999-06-02 | — | — | EP | disclosed |
| EP-0739341-A1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | Novartis AG (CH) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995019358-A1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |