Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19907856 | 0.89 | L3MBTL1 (0.48) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL8304463 | 0.81 | MAPT (0.48) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL8304460 | 0.81 | MAPT (0.48) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL69990 | 0.78 | L3MBTL1 (0.62) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL29416324 | 0.78 | L3MBTL1 (0.62) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL2800466 | 0.76 | L3MBTL1 (0.54) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL519095 | 0.76 | KDM4E (0.67) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL30503698 | 0.76 | KDM4E (0.67) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL30434883 | 0.74 | L3MBTL1 (0.53) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 | |
| SCHEMBL9198739 | 0.74 | L3MBTL1 (0.53) | TDP1L3MBTL1KDM4EALDH1A1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041840-B1 | RILYAZINE DERIVATIVES AND COMPOSITIONS FOR THE TREATMENT OF CANCER | THE WARNER-BABCOCK INST FOR GREEN CHEMISTRY LLC (US) | 2018-02-28 | — | — | EP | disclosed |