Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.96 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.96 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.96 |
| ▸ | MAPT | P10636 | 1/20 | 0.96 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304538 | 1.00 | GAPDH (0.96) | GAPDHTRPA1DDAH1MAPTPPARG | |
| SCHEMBL28058254 | 1.00 | GAPDH (0.96) | GAPDHTRPA1DDAH1MAPTPPARG | |
| SCHEMBL8309540 | 1.00 | GAPDH (0.96) | GAPDHTRPA1DDAH1MAPTPPARG | |
| SCHEMBL8309537 | 1.00 | GAPDH (0.96) | GAPDHTRPA1DDAH1MAPTPPARG | |
| 4-Hydroxynon-2-Enal SCHEMBL3920 | 0.98 | GAPDH (1.00) | GAPDHTRPA1DDAH1MAPTPPARG | |
| 4-Hydroxynon-2-Enal SCHEMBL2890600 | 0.98 | GAPDH (1.00) | GAPDHTRPA1DDAH1MAPTPPARG | |
| 4-Hydroxynon-2-Enal SCHEMBL2890601 | 0.98 | GAPDH (1.00) | GAPDHTRPA1DDAH1MAPTPPARG | |
| 4-Hydroxynon-2-Enal SCHEMBL30767210 | 0.98 | GAPDH (1.00) | GAPDHTRPA1DDAH1MAPTPPARG | |
| 4-Hydroxynon-2-Enal SCHEMBL3921 | 0.98 | GAPDH (1.00) | GAPDHTRPA1DDAH1MAPTPPARG | |
| 4-Hydroxynon-2-Enal SCHEMBL2267834 | 0.96 | GAPDH (0.96) | GAPDHTRPA1DDAH1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105572253-A | Method for detecting 4-HHE and 4-HNE in oil through high performance liquid chromatography | UNIV SHANGHAI JIAOTONG | 2016-05-11 | — | — | CN | disclosed |
| EP-0650599-B1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS ISLE OF MAN LIMITED (GB) | 1999-11-03 | — | — | EP | disclosed |
| US-5726063-A | Method of colorimetric analysis of malonic dialdehyde and 4-hydroxy-2-enaldehydes as indexes of lipid peroxidation, kits for carrying out said method, substituted indoles for use in said method and their preparation | OXIS ISLE OF MAN, LIMITED (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0650599-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS INTERNATIONAL S.A. (FR) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994027155-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | BIOXYTECH (FR) | 1994-11-24 | — | — | WO | disclosed |