Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 12/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308388 | 0.82 | KMO (0.62) | KMOKDM4ETDP1NPC1RAB9A | |
| SCHEMBL8305333 | 0.80 | KDM4E (0.59) | KDM4ETDP1MAPTTSHRSMO | |
| SCHEMBL8304580 | 0.78 | KDM4E (0.53) | KMOKDM4ETDP1MAPTMEN1 | |
| SCHEMBL15569110 | 0.75 | KDM4E (0.53) | KMOKDM4ETDP1TP53MAPT | |
| SCHEMBL25780881 | 0.72 | KDM4E (0.80) | KDM4ETDP1MAPTNPC1TSHR | |
| SCHEMBL23354547 | 0.71 | FTO (0.53) | KMOKDM4ETSHREIF4E | |
| SCHEMBL15569130 | 0.71 | KDM4E (0.62) | KDM4ETDP1TP53MAPTMEN1 | |
| SCHEMBL15567980 | 0.69 | KDM4E (0.54) | KMOKDM4ETDP1MAPTMEN1 | |
| SCHEMBL17201766 | 0.69 | KDM4E (0.58) | KMOKDM4ETDP1MAPTMEN1 | |
| SCHEMBL22641581 | 0.69 | KMO (0.73) | KMOKDM4ETP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739341-B1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | NOVARTIS AG (CH) | 1999-06-02 | — | — | EP | disclosed |
| EP-0739341-A1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | Novartis AG (CH) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995019358-A1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |