Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784774 | 0.76 | DRD2 (0.55) | HTR4ACHEDRD2HTR1AMEN1 | |
| SCHEMBL8304633 | 0.72 | DRD2 (0.44) | HTR4ACHEDRD2GRM2MEN1 | |
| SCHEMBL6716473 | 0.71 | DRD2 (0.42) | DRD2HTR2AMEN1KMT2A | |
| SCHEMBL7029357 | 0.70 | QDPR (0.52) | DRD2HTR2AMEN1KMT2A | |
| SCHEMBL7938441 | 0.69 | KDM4E (0.46) | HTR2A | |
| SCHEMBL6717514 | 0.69 | EHMT2 (0.42) | DRD2HTR2AMEN1KMT2A | |
| SCHEMBL6815771 | 0.69 | MEN1 (0.45) | TRPC6MEN1KMT2A | |
| SCHEMBL6924205 | 0.68 | ABCB1 (0.43) | DRD2SIGMAR1 | |
| SCHEMBL7880812 | 0.68 | HTR2A (0.47) | HTR2AHTR1A | |
| Water SCHEMBL6827475 | 0.67 | EHMT2 (0.41) | DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |