Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957258 | 0.81 | DPP4 (0.38) | MEN1KMT2AL3MBTL1NPC1PKM | |
| SCHEMBL8308129 | 0.80 | — | — | |
| SCHEMBL9200767 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2ANPC1PKMRAB9A | |
| SCHEMBL8308653 | 0.69 | RIPK1 (0.34) | L3MBTL1 | |
| SCHEMBL27260466 | 0.64 | KDM4E (0.39) | KMT2ANPC1PKMRAB9A | |
| SCHEMBL8957126 | 0.63 | NPC1 (0.42) | HTTNPC1PKM | |
| SCHEMBL10972566 | 0.62 | ALDH1A1 (0.48) | MEN1KMT2ACUL4ATYMS | |
| SCHEMBL18490147 | 0.62 | CYP1A2 (0.37) | HTTNPC1 | |
| SCHEMBL23990453 | 0.61 | CYP1A2 (0.42) | HTTNPC1 | |
| SCHEMBL16571753 | 0.61 | HTT (0.48) | MEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638074-B1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| WO-1993022295-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |