Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305864 | 0.87 | KDM4E (0.33) | RIPK1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8308129 | 0.78 | — | — | |
| SCHEMBL2696901 | 0.76 | ALDH1A1 (0.44) | RIPK1ALDH1A1EPHX1KDM4EGLA | |
| SCHEMBL8957108 | 0.74 | DPP4 (0.34) | RIPK1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL933947 | 0.73 | ALDH1A1 (0.41) | RIPK1ALDH1A1EPHX1KDM4EGLA | |
| SCHEMBL9216232 | 0.72 | RIPK1 (0.39) | RIPK1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL9203070 | 0.70 | GABRA5 (0.38) | RIPK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL755172 | 0.70 | CHRNA4 (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL8304861 | 0.69 | MEN1 (0.31) | L3MBTL1 | |
| SCHEMBL9204335 | 0.68 | ALDH1A1 (0.36) | RIPK1ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638074-B1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0638074-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF Aktiengesellschaft (DE) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993022295-A1 | ISOXAZOLE CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |